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Prof. Dr. Ruth Freitag

Prof. Dr. Ruth Freitag


Process Biotechnology


Selected publications

2023

Leitner, Lisa-Cathrin; Schneider, Rika; Steiner, Thomas; Stenzel, Martina H.; Freitag, Ruth; Greiner, Andreas
Efficient Synthesis and Wetting Characteristics of Amphiphilic Galactose-PLA Block Copolymers : ...
in Macromolecular Chemistry and Physics volume 224 (2023) issue 1
doi:10.1002/macp.202100431 ...

2022

Jasinski, Julia; Wilde, Magdalena V.; Völkl, Matthias; Jérôme, Valérie; Fröhlich, Thomas; Freitag, Ruth; Scheibel, Thomas
Tailor-Made Protein Corona Formation on Polystyrene Microparticles and its Effect on Epithelial ...
in ACS Applied Materials & Interfaces volume 14 (2022) issue 41. - page 47277-47287
doi:10.1021/acsami.2c13987 ...

Liao, Xiaojian; Jérôme, Valérie; Agarwal, Seema; Freitag, Ruth; Greiner, Andreas
High Strength and High Toughness Electrospun Multifibrillar Yarns with Highly Aligned Hierarchy ...
in Macromolecular Bioscience (2022)
doi:10.1002/mabi.202200291 ...

Steiner, Thomas; Möller, Julia N.; Löder, Martin G. J.; Hilbrig, Frank; Laforsch, Christian; Freitag, Ruth
Microplastic Contamination of Composts and Liquid Fertilizers from Municipal Biowaste Treatment ...
in Waste and Biomass Valorization (2022)
doi:10.1007/s12649-022-01870-2 ...

Schöpfer, Lion; Möller, Julia N.; Steiner, Thomas; Schnepf, Uwe; Marhan, Sven; Resch, Julia; Bayha, Ansilla; Löder, Martin G. J.; Freitag, Ruth; Brümmer, Franz; Laforsch, Christian; Streck, Thilo; Forberger, Jens; Kranert, Martin; Kandeler, Ellen; Pagel, Holger
Microplastics persist in an arable soil but do not affect soil microbial biomass, enzyme activi ...
in Journal of Plant Nutrition and Soil Science (2022)
doi:10.1002/jpln.202200062 ...

Steiner, Thomas; Zhang, Yuanhu; Möller, Julia N.; Agarwal, Seema; Löder, Martin G. J.; Greiner, Andreas; Laforsch, Christian; Freitag, Ruth
Municipal biowaste treatment plants contribute to the contamination of the environment with res ...
in Scientific Reports volume 12 (2022) issue 1
doi:10.1038/s41598-022-12912-z ...

Helm, Moritz; Huang, Songyan Ben; Gollner, Katrin; Gollner, Ulrich; Jérôme, Valérie; Freitag, Ruth
Cultivation of Encapsulated Primary Human B Lymphocytes : A First Step toward a Bioartificial G ...
in Macromolecular Bioscience (2022)
doi:10.1002/mabi.202200256 ...

Müller, Ann-Kathrin; Brehm, Julian; Völkl, Matthias; Jérôme, Valérie; Laforsch, Christian; Freitag, Ruth; Greiner, Andreas
Disentangling biological effects of primary nanoplastics from dispersion paints' additional com ...
in Ecotoxicology and Environmental Safety volume 242 (2022)
doi:10.1016/j.ecoenv.2022.113877 ...

Simeon, Meshack Imologie; Herkendell, Katharina; Pant, Deepak; Freitag, Ruth
Electrochemical evaluation of different polymer binders for the production of carbon-modified s ...
in Chemical Engineering Journal Advances volume 10 (2022)
doi:10.1016/j.ceja.2022.100246 ...

Simeon, Meshack Imologie; Freitag, Ruth
Influence of electrode spacing and fed-batch operation on the maximum performance trend of a so ...
in International Journal of Hydrogen Energy volume 47 (2022) issue 24. - page 12304-12316
doi:10.1016/j.ijhydene.2021.11.110 ...

Mlinar, Stanislava; Weig, Alfons; Freitag, Ruth
Influence of NH₃ and NH₄⁺ on anaerobic digestion and microbial population structure at increasi ...
in Bioresource Technology (2022)
doi:10.1016/j.biortech.2022.127638 ...

Simeon, Meshack Imologie; Weig, Alfons; Freitag, Ruth
Optimization of soil microbial fuel cell for sustainable bio-electricity production: combined e ...
in Biotechnology for Biofuels and Bioproducts volume 15 (2022)
doi:10.1186/s13068-022-02224-9 ...

Völkl, Matthias; Jérôme, Valérie; Weig, Alfons; Jasinski, Julia; Meides, Nora; Strohriegl, Peter; Scheibel, Thomas; Freitag, Ruth
Pristine and artificially-aged polystyrene microplastic particles differ in regard to cellular ...
in Journal of Hazardous Materials volume 435 (2022)
doi:10.1016/j.jhazmat.2022.128955 ...

Riedl, Simon; Jérôme, Valérie; Freitag, Ruth
Repeated Transient Transfection : An Alternative for the Recombinant Production of Difficult-to ...
in Processes volume 10 (2022) issue 6
doi:10.3390/pr10061064 ...

Ramsperger, Anja; Jasinski, Julia; Völkl, Matthias; Witzmann, Thomas; Meinhart, Marcel; Jérôme, Valérie; Kretschmer, Winfried; Freitag, Ruth; Senker, Jürgen; Fery, Andreas; Kress, Holger; Scheibel, Thomas; Laforsch, Christian
Supposedly identical microplastic particles substantially differ in their material properties i ...
in Journal of Hazardous Materials volume 425 (2022)
doi:10.1016/j.jhazmat.2021.127961 ...

2021

Diaz Ariza, Ivonne L.; Jérôme, Valérie; Pérez Pérez, León D.; Freitag, Ruth
Amphiphilic Graft Copolymers Capable of Mixed-Mode Interaction as Alternative Nonviral Transfec ...
in ACS Applied Bio Materials volume 4 (2021) issue 2. - page 1268-1282
doi:10.1021/acsabm.0c01123 ...

Simeon, Meshack Imologie; Imoize, Agbotiname Lucky; Freitag, Ruth
Comparative evaluation of the performance of a capacitive and a non-capacitive microbial fuel c ...
18th International Multi-Conference on Systems, Signals & Devices (SSD 2021)
Piscataway, NJ : IEEE, 2021. - page 1076-1082
doi:10.1109/SSD52085.2021.9429481 ...

Diaz, Ivonne L.; Jérôme, Valérie; Freitag, Ruth; Perez, León D.
Development of poly(ethyleneimine) grafted amphiphilic copolymers : Evaluation of their cytotox ...
in Journal of Bioactive and Compatible Polymers volume 36 (2021) issue 6. - page 447-463
doi:10.1177/08839115211053925 ...

Keim, Daniel; Gollner, Katrin; Gollner, Ulrich; Jérôme, Valérie; Freitag, Ruth
Generation of Recombinant Primary Human B Lymphocytes Using Non-Viral Vectors
in International Journal of Molecular Sciences volume 22 (2021) issue 15
doi:10.3390/ijms22158239 ...

Riedl, Simon; Völkl, Matthias; Holzinger, Anja; Jasinski, Julia; Jérôme, Valérie; Scheibel, Thomas; Feldhaar, Heike; Freitag, Ruth
In vitro cultivation of primary intestinal cells from Eisenia fetida as basis for ecotoxicologi ...
in Ecotoxicology volume 31 (2021) . - page 221-233
doi:10.1007/s10646-021-02495-2 ...

Helm, Moritz; Riedl, Simon; Gollner, Katrin; Gollner, Ulrich; Jérôme, Valérie; Freitag, Ruth
Isolation of primary human B lymphocytes from tonsils compared to blood as alternative source f ...
in Journal of Chromatography B volume 1179 (2021)
doi:10.1016/j.jchromb.2021.122853 ...

Rudolph, Julia; Völkl, Matthias; Jérôme, Valérie; Scheibel, Thomas; Freitag, Ruth
Noxic effects of polystyrene microparticles on murine macrophages and epithelial cells
in Scientific Reports volume 11 (2021)
doi:10.1038/s41598-021-95073-9 ...

Rosenfeldt, Sabine; Mickoleit, Frank; Jörke, Cornelia; Clement, Joachim H.; Markert, Simon; Jérôme, Valérie; Schwarzinger, Stephan; Freitag, Ruth; Schüler, Dirk; Uebe, René; Schenk, Anna
Towards standardized purification of bacterial magnetic nanoparticles for future in vivo applic ...
in Acta Biomaterialia volume 120 (2021) . - page 293-303
doi:10.1016/j.actbio.2020.07.042 ...

2020

Weithmann, Nicolas; Mlinar, Stanislava; Sonnleitner, Eva; Weig, Alfons; Freitag, Ruth
Flexible feeding in anaerobic digestion – Impact on process stability, performance and microbia ...
in Anaerobe (2020)
doi:10.1016/j.anaerobe.2020.102297 ...

Riese, Cornelius N.; Uebe, René; Rosenfeldt, Sabine; Schenk, Anna; Jérôme, Valérie; Freitag, Ruth; Schüler, Dirk
An automated oxystat fermentation regime for microoxic cultivation of Magnetospirillum gryphisw ...
in Microbial Cell Factories volume 19 (2020) . - page No. 206
doi:10.1186/s12934-020-01469-z ...

Mickoleit, Frank; Jérôme, Valérie; Freitag, Ruth; Schüler, Dirk
Bacterial Magnetosomes as Novel Platform for the Presentation of Immunostimulatory, Membrane-Bo ...
in Advanced Biosystems volume 4 (2020) issue 3
doi:10.1002/adbi.201900231 ...

Mlinar, Stanislava; Weig, Alfons; Freitag, Ruth
Influence of mixing and sludge volume on stability, reproducibility, and productivity of labora ...
in Bioresource Technology Reports volume 11 (2020)
doi:10.1016/j.biteb.2020.100444 ...

Mader, Michael; Helm, Moritz; Lu, Mingxia; Stenzel, Martina H.; Jérôme, Valérie; Agarwal, Seema; Freitag, Ruth; Greiner, Andreas
Perfusion Cultivation of Artificial Liver ECM in Fibrous Polymer Sponges Biomimicking Scaffolds ...
in Biomacromolecules volume 21 (2020) issue 10. - page 4094-4104
doi:10.1021/acs.biomac.0c00900 ...

Simeon, Meshack Imologie; Asoiro, Felix U.; Aliyu, Mohamad; Raji, Olayinka A.; Freitag, Ruth
Polarization and power density trends of a soil-based microbial fuel cell treated with human ur ...
in International Journal of Energy Research volume 44 (2020) issue 7. - page 5968-5976
doi:10.15495/EPub_UBT_00005040 ...

Diaz, Ivonne L.; Sierra, Cesar A.; Jérôme, Valérie; Freitag, Ruth; Perez, León D.
Target grafting of poly(2-(dimethylamino)ethyl methacrylate) to biodegradable block copolymers
in Journal of Polymer Science volume 58 (2020) issue 16. - page 2168-2180
doi:10.1002/pol.20200204 ...

Jérôme, Valérie; Synatschke, Christopher V.; Freitag, Ruth
Transient Destabilization of Biological Membranes Contributes to the Superior Performance of St ...
in ACS Omega volume 5 (2020) issue 41. - page 26640-26654
doi:10.1021/acsomega.0c03367 ...

2019

Weithmann, Nicolas; Mlinar, Stanislava; Hilbrig, Frank; Bachmaf, Samer; Arndt, Julia; Planer-Friedrich, Britta; Weig, Alfons; Freitag, Ruth
Arsenic metabolism in technical biogas plants : possible consequences for resident microbiota a ...
in AMB Express volume 9 (2019)
doi:10.1186/s13568-019-0902-6 ...

Reich, Steffen; Kaiser, Patrick; Mafi, Mahsa; Schmalz, Holger; Rhinow, Daniel; Freitag, Ruth; Greiner, Andreas
High‐Temperature Spray‐Dried Polymer/Bacteria Microparticles for Electrospinning of Composite N ...
in Macromolecular Bioscience volume 19 (2019) issue 5
doi:10.1002/mabi.201800356 ...

Jérôme, Valérie; Freitag, Ruth; Schüler, Dirk; Mickoleit, Frank
SEAP activity measurement in reporter cell-based assays using BCIP / NBT as substrate
in Analytical Biochemistry volume 585 (2019)
doi:10.1016/j.ab.2019.113402 ...

2018

Chen, Baizhu; Synatschke, Christopher V.; Jérôme, Valérie; Müller, Axel H. E.; Freitag, Ruth; Wu, Chi
Co-transfection of star-shaped PDMAEMAs enhance transfection efficiency of protamine/pDNA compl ...
in European Polymer Journal volume 103 (2018) . - page 362-369
doi:10.1016/j.eurpolymj.2018.04.022 ...

Riedl, Simon; Kaiser, Patrick; Raup, Alexander; Synatschke, Christopher V.; Jérôme, Valérie; Freitag, Ruth
Non-Viral Transfection of Human T Lymphocytes
in Processes volume 6 (2018) issue 10
doi:10.3390/pr6100188 ...

Stoppok, Manfred; Jess, Andreas; Freitag, Ruth; Alber, Erdmute
Of culture, consumption and cost : A comparative Analysis of household energy consumption in Ke ...
in Energy Research & Social Science volume 40 (2018) . - page 127-139
doi:10.1016/j.erss.2017.12.004 ...

Weithmann, Nicolas; Möller, Julia N.; Löder, Martin G. J.; Piehl, Sarah; Laforsch, Christian; Freitag, Ruth
Organic fertilizer as a vehicle for the entry of microplastic into the environment
in Science Advances volume 4 (2018) issue 4
doi:10.1126/sciadv.aap8060 ...

Pretscher, Martin; Pineda-Contreras, Beatriz A.; Kaiser, Patrick; Reich, Steffen; Schöbel, Judith; Kuttner, Christian; Freitag, Ruth; Fery, Andreas; Schmalz, Holger; Agarwal, Seema
pH-Responsive Biohybrid Carrier Material for Phenol Decontamination in Wastewater
in Biomacromolecules volume 19 (2018) issue 8. - page 3224-3232
doi:10.1021/acs.biomac.8b00361 ...

Kaiser, Patrick; Reich, Steffen; Greiner, Andreas; Freitag, Ruth
Preparation of Biocomposite Microfibers Ready for Processing into Biologically Active Textile F ...
in Macromolecular Bioscience volume 18 (2018) issue 7
doi:10.1002/mabi.201800046 ...

Kaiser, Patrick; Werner, Melanie; Jérôme, Valérie; Freitag, Ruth
Scale‐up of the ex vivo expansion of encapsulated primary human T lymphocytes
in Biotechnology and Bioengineering volume 115 (2018) issue 10. - page 2632-2642
doi:10.1002/bit.26786 ...

Mader, Michael; Jérôme, Valérie; Freitag, Ruth; Agarwal, Seema; Greiner, Andreas
Ultraporous, compressible, wettable polylactide/polycaprolactone sponges for tissue engineering
in Biomacromolecules volume 19 (2018) issue 5. - page 1663-1673
doi:10.1021/acs.biomac.8b00434 ...

2017

Raup, Alexander; Wang, Hui; Synatschke, Christopher V.; Jérôme, Valérie; Agarwal, Seema; Pergushov, Dmitry V.; Müller, Axel H. E.; Freitag, Ruth
Compaction and transmembrane delivery of pDNA : differences between l-PEI and two types of amph ...
in Biomacromolecules volume 18 (2017) issue 3. - page 808-818
doi:10.1021/acs.biomac.6b01678 ...

Jérôme, Valérie; Thoring, Lena; Salzig, Denise; Kubick, Stefan; Freitag, Ruth
Comparison of cell-based versus cell-free mammalian systems for the production of a recombinant ...
in Engineering in Life Sciences volume 17 (2017) issue 10. - page 1097-1107
doi:10.1002/elsc.201700005 ...

Jérôme, Valérie; Werner, Melanie; Kaiser, Patrick; Freitag, Ruth
Creating a Biomimetic Microenvironment for the Ex Vivo Expansion of Primary Human T Lymphocytes
in Macromolecular Bioscience volume 17 (2017) issue 9
doi:10.1002/mabi.201700091 ...

Kaiser, Patrick; Reich, Steffen; Leykam, Daniel; Willert-Porada, Monika; Greiner, Andreas; Freitag, Ruth
Electrogenic Single-Species Biocomposites as Anodes for Microbial Fuel Cells
in Macromolecular Bioscience volume 17 (2017) issue 7
doi:10.1002/mabi.201600442 ...

Stahlschmidt, Ullrich; Jérôme, Valérie; Majewski, Alexander P.; Müller, Axel H. E.; Freitag, Ruth
Systematic Study of a Library of PDMAEMA-Based, Superparamagnetic Nano-Stars for the Transfecti ...
in Polymers volume 9 (2017) issue 5
doi:10.3390/polym9050156 ...

2016

Weithmann, Nicolas; Weig, Alfons; Freitag, Ruth
Process parameters and changes in the microbial community patterns during the first 240 days of ...
in AMB Express volume 6 (2016) issue 1. - page No. 53
doi:10.1186/s13568-016-0219-7 ...

Raup, Alexander; Stahlschmidt, Ullrich; Jérôme, Valérie; Synatschke, Christopher V.; Müller, Axel H. E.; Freitag, Ruth
Influence of Polyplex Formation on the Performance of Star-Shaped Polycationic Transfection Agen ...
in Polymers volume 8 (2016) issue 6
doi:10.3390/polym8060224 ...

Zambrano, Kenny; Jérôme, Valérie; Freitag, Ruth; Buchholz, Rainer; Jäck, Hans-Martin; Hübner, Holger; Schuh, Wolfgang
Prolonged Ex vivo expansion and differentiation of naïve murine CD43− B splenocytes
in Biotechnology Progress volume 32 (2016) issue 4. - page 978-989
doi:10.1002/btpr.2265 ...

Raup, Alexander; Jérôme, Valérie; Freitag, Ruth; Synatschke, Christopher V.; Müller, Axel H. E.
Promoter, transgene, and cell line effects in the transfection of mammalian cells using PDMAEMA ...
in Biotechnology Reports volume 11 (2016) . - page 53-61
doi:10.1016/j.btre.2016.05.003 ...

2015

Shi, Yinfeng; Zhou, Peiran; Jérôme, Valérie; Freitag, Ruth; Agarwal, Seema
Enzymatically Degradable Polyester-Based Adhesives
in ACS Biomaterials Science & Engineering volume 1 (2015) issue 10. - page 971-977
doi:10.1021/acsbiomaterials.5b00217 ...

Werner, Melanie; Schmoldt, Daria; Hilbrig, Frank; Jérôme, Valérie; Raup, Alexander; Zambrano, Kenny; Hübner, Holger; Buchholz, Rainer; Freitag, Ruth
High Cell Density Cultivation of Human Leukemia T Cells (Jurkat Cells) in Semipermeable Polyele ...
in Engineering in Life Sciences volume 15 (2015) issue 4. - page 357-367
doi:10.1002/elsc.201400186 ...

Käfer, Florian; Liu, Fangyao; Stahlschmidt, Ullrich; Jérôme, Valérie; Freitag, Ruth; Karg, Matthias; Agarwal, Seema
LCST and UCST in one : Double thermoresponsive behavior of block copolymers of poly(ethylene gl ...
in Langmuir volume 31 (2015) issue 32. - page 8940-8946
doi:10.1021/acs.langmuir.5b02006 ...

Knierim, Christian; Enzeroth, Michaela; Kaiser, Patrick; Dams, Christian; Nette, David; Seubert, Andreas; Klingl, Andreas; Greenblatt, Charles; Jérôme, Valérie; Agarwal, Seema; Freitag, Ruth; Greiner, Andreas
Living Composites of Bacteria and Polymers as Biomimetic Films for Metal Sequestration and Bior ...
in Macromolecular Bioscience volume 15 (2015) issue 8. - page 1052-1059
doi:10.1002/mabi.201400538 ...

Pineda Contreras, Paul; Kuttner, Christian; Fery, Andreas; Stahlschmidt, Ullrich; Jérôme, Valérie; Freitag, Ruth; Agarwal, Seema
Renaissance for Low Shrinking Resins : all-in-one Solution by Bi-Functional Vinylcyclopropane-A ...
in Chemical Communications volume 51 (2015) issue 59. - page 11899-11902
doi:10.1039/C5CC03901K ...

Duan, Gaigai; Jiang, Shaohua; Jérôme, Valérie; Wendorff, Joachim H.; Fathi, Amir; Uhm, Jacqueline S.; Altstädt, Volker; Herling, Markus M.; Breu, Josef; Freitag, Ruth; Agarwal, Seema; Greiner, Andreas
Ultralight, Soft Polymer Sponges by Self-Assembly of Short Electrospun Fibers in Colloidal Disp ...
in Advanced Functional Materials volume 25 (2015) issue 19. - page 2850-2856
doi:10.1002/adfm.201500001 ...

2014

Kaiser, Patrick; Werner, Melanie; Jérôme, Valérie; Hübner, Holger; Buchholz, Rainer; Freitag, Ruth
Cell Retention by Encapsulation for the Cultivation of Jurkat Cells in Fixed and Fluidized Bed ...
in Biotechnology and Bioengineering volume 111 (2014) issue 12. - page 2571-2579
doi:10.1002/bit.25304 ...

Freitag, Ruth
Chromatographic techniques in the downstream processing of proteins in biotechnology
Animal cell biotechnology : methods and protocols
New York, NY : Humana Press, 2014. - page 419-458 . - (Methods in Molecular Biology; 1104)
doi:10.1007/978-1-62703-733-4_25 ...

Wang, Hui; Synatschke, Christopher V.; Raup, Alexander; Jérôme, Valérie; Freitag, Ruth; Agarwal, Seema
Oligomeric dual functional antibacterial polycaprolactone
in Polymer Chemistry volume 5 (2014) issue 7. - page 2453-2460
doi:10.1039/C3PY01467C ...

2013

Majewski, Alexander P.; Stahlschmidt, Ullrich; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.; Schmalz, Holger
PDMAEMA-Grafted Core-Shell-Corona Particles for Nonviral Gene Delivery and Magnetic Cell Separa ...
in Biomacromolecules volume 14 (2013) issue 9. - page 3081-3090
doi:10.1021/bm400703d ...

Werner, Melanie; Biss, Karsten; Jérôme, Valérie; Hilbrig, Frank; Freitag, Ruth; Zambrano, Kenny; Hübner, Holger; Buchholz, Rainer; Mahou, Redouan; Wandrey, Christine
Use of the mitochondria toxicity assay for quantifying the viable cell density of microencapsul ...
in Biotechnology Progress volume 29 (2013) issue 4. - page 986-993
doi:10.1002/btpr.1734 ...

2012

Majewski, Alexander P.; Schallon, Anja; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.; Schmalz, Holger
Dual-responsive magnetic core-shell nanoparticles for non-viral gene delivery and cell separati ...
in Abstracts of Papers of the American Chemical Society volume 243 (2012) . - page 40-POLY
Symposium on Ionic Liquids - Science and Applications / 243rd National Spring Meeting of the American-Chemical-Society, San Diego, CA, MAR 25-29, 2012, San Diego, CA,

Majewski, Alexander P.; Schallon, Anja; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.; Schmalz, Holger
Dual-Responsive Magnetic Core-Shell Nanoparticles for Nonviral Gene Delivery and Cell Separatio ...
in Biomacromolecules volume 13 (2012) issue 3. - page 857-866
doi:10.1021/bm2017756 ...

Freimark, Denise; Jérôme, Valérie; Freitag, Ruth
Effect of process parameters and product-host-interaction on hVEGFA-production by recombinant C ...
in Biotechnology Progress volume 28 (2012) issue 3. - page 762-772
doi:10.1002/btpr.1524 ...

Hilbrig, Frank; Freitag, Ruth
Isolation and purification of recombinant proteins, antibodies and plasmid DNA with hydroxyapat ...
in Biotechnology Journal volume 7 (2012) issue 1. - page 90-102
doi:10.1002/biot.201100015 ...

Schallon, Anja; Synatschke, Christopher V.; Jérôme, Valérie; Müller, Axel H. E.; Freitag, Ruth
Nanoparticulate Nonviral Agent for the Effective Delivery of pDNA and siRNA to Differentiated C ...
in Biomacromolecules volume 13 (2012) issue 11. - page 3463-3474
doi:10.1021/bm3012055 ...

Freitag, Ruth; Jérôme, Valérie; Müller, Axel H. E.; Schmalz, Holger
Polymermodifizierte magnetische Nanopartikel
in GIT : Labor-Fachzeitschrift volume 56 (2012) issue 8. - page 602
https://www.git-labor.de/forschung/life-sciences-b ...

2011

Arnold, Marc; Bittermann, Holger; Kalbfuss-Zimmermann, Bernd; Neumann, Thomas; Schmidt, Kristina; Sekul, Renate; Hilbrig, Frank; Ludolph, Heiko; Freitag, Ruth
Antibody purification by affinity chromatography based on small molecule affinity ligands ident ...
in Journal of Chromatography A volume 1218 (2011) issue 29. - page 4649-4659
doi:10.1016/j.chroma.2011.05.040 ...

Schallon, Anja; Synatschke, Christopher V.; Pergushov, Dmitry V.; Jérôme, Valérie; Müller, Axel H. E.; Freitag, Ruth
DNA Melting Temperature Assay for Assessing the Stability of DNA Polyplexes Intended for Nonvir ...
in Langmuir volume 27 (2011) issue 19. - page 12042-12051
doi:10.1021/la201803c ...

Synatschke, Christopher V.; Schallon, Anja; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.
Influence of Polymer Architecture and Molecular Weight of Poly(2-(dimethylamino)ethyl methacryl ...
in Biomacromolecules volume 12 (2011) issue 12. - page 4247-4255
doi:10.1021/bm201111d ...

Pfaff, André; Schallon, Anja; Ruhland, Thomas M.; Majewski, Alexander P.; Schmalz, Holger; Freitag, Ruth; Müller, Axel H. E.
Magnetic and Fluorescent Glycopolymer Hybrid Nanoparticles for Intranuclear Optical Imaging
in Biomacromolecules volume 12 (2011) issue 10. - page 3805-3811
doi:10.1021/bm201051p ...

2010

Jung, Christoph; Polier, Sigrun; Schöffel, Markus; Drechsler, Markus; Jérôme, Valérie; Freitag, Ruth
Fluorescence Correlation Spectroscopy as a Quantitative Tool Applied to Drug Delivery Model Sys ...
in Nature Precedings (2010)
doi:10.1038/npre.2010.4140.1 ...

Müllner, Markus; Schallon, Anja; Walther, Andreas; Freitag, Ruth; Müller, Axel H. E.
Clickable, Biocompatible, and Fluorescent Hybrid Nanoparticles for Intracellular Delivery and O ...
in Biomacromolecules volume 11 (2010) issue 2. - page 390-396
doi:10.1021/bm901099p ...

Freimark, Denise; Jérôme, Valérie; Freitag, Ruth
A GFP-based method facilitates clonal selection of transfected CHO cells
in Biotechnology Journal volume 5 (2010) issue 1. - page 24-31
doi:10.1002/biot.200800264 ...

2009

Hofstetter, Eugen-Maria; Gabler, Ralf; Peiffer, Stefan; Hilbrig, Frank; Freitag, Ruth
Ammoniakstrippung an einer etablierten, thermophilen Biogasanlage - technische und wirtschaftli ...
in Chemie Ingenieur Technik volume 81 (2009) issue 7. - page 921-932
doi:10.1002/cite.200900033 ...

Jérôme, Valérie; Heider, Andreas; Schallon, Anja; Freitag, Ruth
Exhaustive in vivo labelling of plasmid DNA with BrdU for intracellular detection in non-viral ...
in Biotechnology Journal volume 4 (2009) issue 10. - page 1479-1487
doi:10.1002/biot.200900053 ...

Weiss, Agnes; Jérôme, Valérie; Burghardt, Diana; Likke, Likke; Peiffer, Stefan; Hofstetter, Eugen-Maria; Gabler, Ralf; Freitag, Ruth
Investigation of factors influencing biogas production in a large-scale thermophilic municipal ...
in Applied Microbiology and Biotechnology volume 84 (2009) issue 5. - page 987-1001
doi:10.1007/s00253-009-2093-6 ...

Schubert, Sven; Freitag, Ruth
Investigation of the interaction mechanism of the recombinant human antibody MDJ8 and its fragm ...
in Journal of Chromatography A volume 1216 (2009) issue 18. - page 3831-3840
doi:10.1016/j.chroma.2009.02.074 ...

Hilbrig, Frank; Jérôme, Valérie; Salzig, Mark; Freitag, Ruth
Strategy for the isolation of native dehydrogenases with potential for biosensor development fr ...
in Journal of Chromatography A volume 1216 (2009) issue 16. - page 3518-3525
doi:10.1016/j.chroma.2008.09.020 ...

Parisot, Judicaël; Kurz, Katrin; Hilbrig, Frank; Freitag, Ruth
Use of azobenzene amino acids as photo-responsive conformational switches to regulate antibody– ...
in Journal of Separation Science volume 32 (2009) issue 10. - page 1613-1624
doi:10.1002/jssc.200800698 ...

2008

Achmann, Sabine; Hermann, Markus; Hilbrig, Frank; Jérôme, Valérie; Hämmerle, Martin; Freitag, Ruth; Moos, Ralf
Direct detection of formaldehyde in air by a Novel NAD⁺- and glutathione-independent formaldehy ...
in Talanta volume 75 (2008) issue 3. - page 786-791
doi:10.1016/j.talanta.2007.12.015 ...

Weiss, Agnes; Jérôme, Valérie; Freitag, Ruth; Mayer, Helmut K.
Diversity of the resident microbiota in a thermophilic municipal biogas plant
in Applied Microbiology and Biotechnology volume 81 (2008) issue 1. - page 163-173
doi:10.1007/s00253-008-1717-6 ...

Stocker-Majd, Gisela; Hilbrig, Frank; Freitag, Ruth
Extraction of haemoglobin from human blood by affinity precipitation using a haptoglobin-based ...
in Journal of Chromatography A volume 1194 (2008) issue 1. - page 57-65
doi:10.1016/j.chroma.2008.03.091 ...

Stocker, Gisela; Dumoulin, Dorothée; Vandevyver, Caroline; Hilbrig, Frank; Freitag, Ruth
Screening of a human antibody phage display library against a peptide antigen using stimuli-res ...
in Biotechnology Progress volume 24 (2008) issue 6. - page 1314-1324
doi:10.1002/btpr.60 ...

Freitag, Ruth; Hilbrig, Frank
Use of the avidin (imino)biotin system as a general approach to affinity precipitation
Avidin-Biotin interactions : methods and applications
Totowa, NJ : Humana Press, 2008. - page 35-50 . - (Methods in Molecular Biology; 418)

2007

Freitag, Ruth; Schumacher, Ivo; Hilbrig, Frank
Affinity precipitation an option for early capture in bioprocessing
in Biotechnology Journal volume 2 (2007) issue 6. - page 685-690
doi:10.1002/biot.200600200 ...

Willert-Porada, Monika; Lorenz, Katrin; Freitag, Ruth; Jérôme, Valérie; Pfeiffer, Stefan
Biofilm Based Microbial Fuel Cell
NSTI Nanotech 2007
Boston, Mass. : Nano Science and Technology Institute, 2007. - page 728-731
http://www.nsti.org/publications/Nanotech/2007/pdf ...

Schubert, Sven; Freitag, Ruth
Comparison of ceramic hydroxy- and fluoroapatite versus Protein A/G-based resins in the isolati ...
in Journal of Chromatography A volume 1142 (2007) issue 1. - page 106-113
doi:10.1016/j.chroma.2006.08.075 ...

Weiss, Agnes; Jérôme, Valérie; Freitag, Ruth
Comparison of strategies for the isolation of PCR-compatible, genomic DNA from a municipal biog ...
in Journal of Chromatography B volume 853 (2007) issue 1-2. - page 190-197
doi:10.1016/j.jchromb.2007.03.009 ...

Jérôme, Valérie; Hermann, Markus; Hilbrig, Frank; Freitag, Ruth
Development of a fed-batch process for the production of a dye-linked formaldehyde dehydrogenas ...
in Applied Microbiology and Biotechnology volume 77 (2007) issue 4. - page 779-788
doi:10.1007/s00253-007-1218-z ...

O'Mahony, Kevin; Freitag, Ruth; Hilbrig, Frank; Schumacher, Ingo; Müller, Patrick
Integration of bacteria capture via filtration and in situ lysis for recovery of plasmid DNA un ...
in Biotechnology Progress volume 23 (2007) issue 4. - page 895-903
doi:10.1021/bp0701113 ...

Vandevyver, Caroline; Canarelli, Stéphane; Bossen, Claudia; Fisch, Igor; Motmans, Kris; Raus, Jef; Freitag, Ruth
Investigation and molecular mimicry of the antigen involved in the interaction between the mono ...
in Biotechnology and Bioengineering volume 97 (2007) issue 4. - page 721-734
doi:10.1002/bit.21276 ...

Achmann, Sabine; Hermann, Markus; Jérôme, Valérie; Hämmerle, Martin; Freitag, Ruth; Moos, Ralf
NAD-unabhängige Formaldehyddehydrogenase aus H. zavarzinii : Einsatz im Biosensor
2007
5. Deutsches Biosensor Symposium 2007, Bochum, Deutschland

Freitag, Ruth; Hilbrig, Frank
Theory and practical understanding of the migration behavior of proteins and peptides in CE and ...
in Electrophoresis volume 28 (2007) issue 13. - page 2125-2144
doi:10.1002/elps.200600792 ...

2006

O'Mahony, Kevin; Freitag, Ruth; Dhote, Bernhard; Hilbrig, Frank; Müller, Patrick; Schumacher, Ivo
Capture of Bacteria from Fermentation Broth by Body Feed Filtration : A Solved Problem?
in Biotechnology Progress volume 22 (2006) issue 2. - page 471-483
doi:10.1021/bp050302a ...

Pöhner, Claudia; Hilbrig, Frank; Jérôme, Valérie; Freitag, Ruth
Design and Characterization of Stimuli-Responsive FLAG-tag Analogues and the Illumination-Induc ...
in Biotechnology Progress volume 22 (2006) issue 4. - page 1170-1178
doi:10.1021/bp060011h ...

Stocker, Gisela; Vandevyver, Caroline; Hilbrig, Frank; Freitag, Ruth
Purification of RT-PCR Competent Poly(A) mRNA from Crude Cell Lysate by Affinity Precipitation
in Biotechnology Progress volume 22 (2006) issue 6. - page 1621-1629
doi:10.1021/bp060095u ...

2005

Suarez, Mougli; Haenni, Marisa; Canarelli, Stéphane; Fisch, Florian; Chodanowski, Pierre; Servis, Catherine; Michielin, Olivier; Freitag, Ruth; Moreillon, Philippe; Mermod, Nicolas
Structure-Function Characterization and Optimization of a Plant-Derived Antibacterial Peptide
in Antimicrobial Agents and Chemotherapy volume 49 (2005) issue 9. - page 3847-3857
doi:10.1128/AAC.49.9.3847-3857.2005 ...

Jozwik, Magdalena; Kaczmarski, Krzystof; Freitag, Ruth
Investigation of the steric mass action formalism in the simulation of breakthrough curves on a ...
in Journal of Chromatography A volume 1073 (2005) issue 1-2. - page 111-121
doi:10.1016/j.chroma.2005.01.059 ...

Desponds, Arnaud; Freitag, Ruth
Light-responsive bioconjugates as novel tools for specific capture of biologicals by photoaffin ...
in Biotechnology and Bioengineering volume 91 (2005) issue 5. - page 583-591
doi:10.1002/bit.20479 ...

O'Mahony, Kevin; Freitag, Ruth; Hilbrig, Frank; Müller, Patrick; Schumacher, Ivo
Proposal for a better integration of bacterial lysis into the production of plasmid DNA at larg ...
in Journal of Biotechnology volume 119 (2005) issue 2. - page 118-132
doi:10.1016/j.jbiotec.2005.03.020 ...

Yamahata, Christophe; Vandevyver, Caroline; Lacharme, Frederic; Izewska, Paulina; Vogel, Horst; Freitag, Ruth; Gijs, Martin A. M.
Pumping of mammalian cells with a nozzle-diffuser micropump
in Lab on a Chip volume 5 (2005) issue 10. - page 1083-1088
doi:10.1039/B504468E ...

Szekely, Laszlo; Freitag, Ruth
Study of the electroosmotic flow as a means to propel the mobile phase in capillary electrochro ...
in Electrophoresis volume 26 (2005) issue 10. - page 1928-1939
doi:10.1002/elps.200410194 ...

2004

Malinova, Vesela; Freitag, Ruth; Wandrey, Christine
Adsorption of charged macromolecules on oppositely charged porous column materials
in Journal of Chromatography A volume 1036 (2004) issue 1. - page 25-32
doi:10.1016/j.chroma.2003.10.087 ...

Szucs, Veronika; Freitag, Ruth
Comparison of a three-peptide separation by capillary electrochromatography, voltage-assisted l ...
in Journal of Chromatography A volume 1044 (2004) issue 1-2. - page 201-210
doi:10.1016/j.chroma.2004.05.103 ...

Freitag, Ruth
Comparison of the chromatographic behavior of monolithic capillary columns in capillary electro ...
in Journal of Chromatography A volume 1033 (2004) issue 2. - page 267-273
doi:10.1016/j.chroma.2004.01.053 ...

Leiderer, M.; Ponader, Thomas; Schumacher, Matthias; Lauterbach, Anja; Hilgert, Karin; Hermann, Markus; Jérôme, Valérie; Hämmerle, Martin; Moos, Ralf; Freitag, Ruth
Elektrochemischer Enzym-Biosensor zur Detektion von gasförmigem Formaldehyd
2004
DECHEMA/GVC-Jahrestagung 2004, Karlsruhe

Lauterbach, Anja; Leiderer, M.; Ponader, P.; Schumacher, Matthias; Hämmerle, Martin; Moos, Ralf; Hermann, Markus; Jérôme, Valérie; Freitag, Ruth
Untersuchungen einer 'Dye-linked' Formaldehyddehydrogenase aus methylotrophen Bakterien
2004
BioPerspectives 2004, Wiesbaden, Deutschland

Jess, Andreas; Freitag, Ruth
Verfahren und Prozesse - nicht nur vor Gericht
in Spektrum (2004) issue 2. - page 28-31
http://www.neu.uni-bayreuth.de/de/Uni_Bayreuth/Sta ...

2003

Hoegger, Daniela; Freitag, Ruth
Investigation of conditions allowing the synthesis of acrylamide-based monolithic microcolumns ...
in Electrophoresis volume 24 (2003) issue 17. - page 2958-2972
doi:10.1002/elps.200305522 ...

Hilbrig, Frank; Freitag, Ruth
Continuous annular chromatography
in Journal of Chromatography B volume 790 (2003) issue 1-2. - page 1-15
doi:10.1016/S1570-0232(03)00085-0 ...

Costioli, Matteo D.; Fisch, Igor; Garret-Flaudy, Frédéric; Hilbrig, Frank; Freitag, Ruth
DNA purification by triple-helix affinity precipitation
in Biotechnology and Bioengineering volume 81 (2003) issue 5. - page 535-545
doi:10.1002/bit.10497 ...

Hoegger, Daniela; Freitag, Ruth
Investigation of mixed-mode monolithic stationary phases for the analysis of charged amino acid ...
in Journal of Chromatography A volume 1004 (2003) issue 1-2. - page 195-208
doi:10.1016/S0021-9673(03)00563-6 ...

Schmidt, Beata; Wandrey, Christine; Freitag, Ruth
Investigation of particle-based and monolithic columns for cation exchange protein displacement ...
in Journal of Chromatography A volume 1018 (2003) issue 2. - page 155-167
doi:10.1016/S0021-9673(03)01326-8 ...

Hilbrig, Frank; Freitag, Ruth
Protein purification by affinity precipitation
in Journal of Chromatography B volume 790 (2003) issue 1-2. - page 79-90
doi:10.1016/S1570-0232(03)00081-3 ...

2002

Giovannini, Roberto; Freitag, Ruth
Continuous Separation of Multicomponent Protein Mixtures by Annular Displacement Chromatography
in Biotechnology Progress volume 18 (2002) issue 6. - page 1324-1331
doi:10.1021/bp010154y ...

Canarelli, Stéphane; Fisch, Igor; Freitag, Ruth
Hyphenation of multi-dimensional chromatography and mass spectrometry for the at-line-analysis ...
in Journal of Chromatography B volume 775 (2002) issue 1. - page 27-35
doi:10.1016/S1570-0232(02)00286-6 ...

2001

Garret-Flaudy, Frédéric; Freitag, Ruth
Use of the avidin (imino)biotin system as a general approach to affinity precipitation
in Biotechnology and Bioengineering volume 71 (2001) issue 3. - page 223-234
doi:10.1002/1097-0290(2000)71:3<223::AID-BIT1012>3 ...


Process Biotechnology


Prof. Dr. Ruth Freitag

Phone: +49 (0) 921 / 55 - 7371
E-mail: bioprozesstechnik@uni-bayreuth.de
Homepage: Homepage of the Contributor

Webmaster: Beate Heinz-Deuerling

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